Pow.Bio expands biomanufacturing footprint with new Alameda facility

Pow.Bio has announced the opening of a 25,000ft2 biomanufacturing facility in Alameda, California, as it seeks to expand its capabilities in continuous fermentation. Located at Marina Village, the new site is designed to help partners scale their processes efficiently while lowering production costs through AI-enabled fermentation technologies.

The facility features a dual-chamber continuous fermentation system, which allows for real-time process adjustments and increased operational efficiency. Pow.Bio’s proprietary AI-driven platform enables predictive control and autonomous fermentation, reducing process variability and accelerating development timelines. By integrating machine learning into fermentation workflows, the company aims to offer a more cost-effective and scalable solution for bio-based product manufacturing.

Shannon Hall, CEO of Pow.Bio, highlighted the challenges many biomanufacturers face in bringing products to market efficiently. “Many promising bio-products struggle with high production costs and lengthy development cycles that delay commercialization. Our new Alameda facility serves as an active demonstration site for a modern, cost-effective manufacturing solution that is already delivering measurable gains for our partners,” Hall stated.

The company’s expansion includes a dedicated food-grade cleanroom for pilot-scale fermentation and downstream processing. As an FDA-registered facility, the site is designed to meet regulatory standards for food and beverage applications. In addition, Pow.Bio has expanded its downstream processing capabilities, incorporating spray drying and lyophilization to support a diverse range of product finishing requirements.

Pow.Bio’s new site also enhances its scale-up capabilities, allowing companies to transition from early-stage research to larger production volumes. The facility supports development at bench and pilot scales, facilitating a seamless move from gram-scale experiments to manufacturing hundreds of kilograms of product.

“Our advanced demonstration facility is setting a new standard for the industry,” Hall added. “It enables our partners to see immediate benefits in cost and performance, achieving results in weeks rather than months or years. We’re thrilled that our AI-driven production platform is helping bring bio-based products to market faster.”

The company envisions the Alameda facility as a model for how its continuous fermentation system can be deployed globally. Its technology is designed to be integrated with existing infrastructure, offering scalable solutions across multiple industries, including food, agriculture, materials, chemicals, and pharmaceuticals.

Pow.Bio is positioning itself as a key player in the biomanufacturing market by focusing on affordability, accelerated product development, and rapid scale-up. The company’s AI-enabled fermentation system is intended to reduce capital expenditure requirements while enhancing production efficiency, allowing manufacturers to adapt quickly to commercial demands.